Global Clinical Program Lead, Immunology

Global Clinical Product Leader, Immunology

Make a more meaningful contribution. Impact patients’ lives every day.

Contribute to our growing pipeline. Join a place with the commitment, knowledge and backing from the business to continue expanding our pipeline. With one of the broadest and deepest pipelines, we are determined to keep contributing and pushing forward. When we get it right there’s nothing more motivating.

AZ’s vision is to grow and expand the indications and assets in immunology to become a major player in the field. This Global Clinical Program Lead (GCPL) role in Late stage clinical development in Immunology is designed to help deliver on that ambition.

The role - Global Clinical Program Lead, Immunology

The individual is expected to work closely with the Business Development team and the Immunology teams to identify diseases where there remains an unmet medical need and assets to fill that need. In addition, the individual will be responsible for also considering how to develop and deliver clinical trials efficiently for immunological assets where the patient population may be small and care is centered in specialized tertiary centers. The GCPL will report into the VP of Late Stage Immunology Clinical Development.

What you’ll do:

• Responsible for liaising with Business Development team to identify new opportunities for investment in Immunology Assets
• Will be lead clinical reviewer for any Business Development Opportunities for Immunology
• Input into AZ’s strategy for Immunology as a member of the Immunology Disease Area Strategy Team representing Late Stage Immunology Clinical development in conjunction with VP of Immunology
• Input into AZ’s strategy for Immunology by serving as member of the Late Stage Clinical Development Team to identify where there are clinical and commercial opportunities in particular diseases to expand AZ’s footprint

• Leads development in conjunction with VP of Immunology, Patient Engagement Lead and Clinical Ops colleagues, of future clinical operation trial delivery and patient engagement strategy for potential immunologic indications
• Accountable for induction and education of new Global Study Team members. May also contribute to clinical trial improvement workstreams on behalf of the Clinical function.
• Delivery of clinical, scientific, and medical information/query responses to Regulatory Agencies, Ethic Committees, Marketing Companies (MCs), and investigators/sites, and provides clarifications as well as solves clinical, scientific, and medical issues in the Global Study Team
• Clinical representative on indication in Global and Clinical Product Teams and/or sub-teams
• Leads governance interactions in conjunction with or as delegated by the GCH such as DRACs, DRCs, PRCs
• Co-leads the study and program strategy for publication development and approval of publications with the GCH
• May have line management of project study physicians and scientists
• Maintains high degree of understanding and awareness on new and emerging medical development advances in the relevant therapeutic area globally.
• Builds trustworthy relationships with steering committees/executive committees, academic research organizations and clinical research organizations as applicable
• Works with international colleagues and with external Alliance partners on development initiatives and regulatory issues
• Provides guidance for externally sponsored trials in cooperation with regional MCs
• Plays key role in development of the clinical sections of regulatory submission documents and is accountable to GCH for their content
• Provides a leadership role in writing responses to comments/questions of Regulatory Authorities for clinical modules
• Leads as delegated by GCH the strategy for the development of regulatory agency briefing documents (BD) and ensure BD completeness; defend BD positions during regulatory meetings as delegated by GCH

Basic Qualifications

• MD, MBBS, or other equivalent medical degree from an accredited university
• Minimum 5 years’ relevant experience within the immunology, rheumatology, allergy, or autoimmune space
• Knowledge of biostatistics, global regulatory environment, and pharmacovigilance relevant to the role
• Experience in leading or reviewing a clinical program to support an indication: design, clinical development plan and Target Product Profile.
• Good presentation skills and effective communication with internal and external collaborators
• Knowledge and experience to work across projects, with a fast-learning curve when moving into new disease areas

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

The annual base salary for this position ranges from $280,895 - $421,342. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.  In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. 

At AstraZeneca, we are driven by a shared purpose to push the boundaries of science to deliver life-changing medicines. Our dynamic environment fosters innovation, collaboration, and continuous learning. Here, you’ll work alongside some of the brightest minds in the industry, contributing to groundbreaking research that has the potential to impact millions of lives worldwide.

Date Posted

24-Jul-2025

Closing Date

30-Jul-2025

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.